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Parvin MS, Chlebek J, Holkov A, Catapano MC, Lomozov Z, Mackov K, Mladnka P (2022) Interactions of isoquinoline alkaloids with transition metals iron and copper

Y., Kim, Y

Glutathione acts as an anti-oxidant by quenching reactive oxygen species, and is involved in the ascorbateglutathione cycle that eliminates damaging peroxides

While it inhibits fibrosis by activating the Keap1-Nrf2 pathway and downregulating the phosphorylation of Smad3 and STAT3, the interactions among involved signaling pathways (such as PI3K/Akt, MAPK, TGF-, Wnt/-catenin) and their roles at different pathological stages have not been systematically studied

Cysteine also helps synthesize glutathione [6-9]

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